The Internal Revenue Service office for St. Lucie County is in Port St. Lucie, Florida on U.S. Highway 1. The location of the office is:
Internal Revenue Service
7410 South US Hwy. 1
Port St. Lucie, FL 34952
Map
The local number is (772) 340-5606. The national toll free phone number for the IRS is 1-800-829-1040